Clostridium: Transmission difficile?

Clostridium: Transmission difficile?

Clostridium difficile can cause large-scale outbreaks of diarrhea [1,2]. Significant progress has recently been achieved to improve treatment of symptomatic C. difficile disease [3]. But hospitals affected by C. difficile infection still face challenges in the effort to control endemic C. difficile infections, which may be related to overuse of antibiotics (e.g., fluoroquinolones, cephalosporin...

Asymptomatic Clostridium difficile Colonisation and Onward Transmission

INTRODUCTION Combined genotyping/whole genome sequencing and epidemiological data suggest that in endemic settings only a minority of Clostridium difficile infection, CDI, is acquired from other cases. Asymptomatic patients are a potential source for many unexplained cases. METHODS We prospectively screened a cohort of medical inpatients in a UK teaching hospital for asymptomatic C. difficile...

Clostridium : transmission difficile ? HARBARTH , Stéphan Juergen , SAMORE , Matthew H HARBARTH , Stéphan Juergen , SAMORE , Matthew H . Clostridium : transmission difficile ?

clostridium difficile

seventy-five meconium samples were examined for the presence of ci. difficile: 3 strains were isola ted. additionally 45 labora tory animal faeces specimens were tested for the same purpose, a further 2 cases were isolated. these five suspicious strains were identified as ci. difficile acco rding to the tests mentioned in the previous paragraphs. the organisms . isolated here showed the same ch...

Quantifying Transmission of Clostridium difficile within and outside Healthcare Settings

To quantify the effect of hospital and community-based transmission and control measures on Clostridium difficile infection (CDI), we constructed a transmission model within and between hospital, community, and long-term care-facility settings. By parameterizing the model from national databases and calibrating it to C. difficile prevalence and CDI incidence, we found that hospitalized patients...